For the next five years, Miles worked with many of the musicians, although Bill Evans had left to pursue his kind of exploratory jazz along with Sonny Stitt on alto sax on a very successful European tour in 1960. In the early Sixties, others who appeared with the Different incarnations of the Davis group included, Hank Mobley and Wayne Shorter on Tenor sax, Victor Feldman and Herbie Hancock on piano, Ron Carter on bass and Tony Williams on drums. As well as playing with the band, Shorter also contributed some standout compositions, including Nefertiti and Footprints.
He was the best-selling music artist in the United States of the 2000s and the best-selling male music artist in the United States of the 2010s, third overall. Billboard named him the "Artist of the Decade (2000-2009). The Marshall Mathers LP, The Eminem Show, "Lose Yourself", "Love the Way You Lie" and "Not Afraid" have all been certified Diamond or higher by the Recording Industry Association of America Rolling Stone has included him in its lists of the 100 Greatest Artists of All Time and the 100 Greatest Songwriters of All Time. He has won numerous awards, including 15 Grammy Awards, eight American Music Awards, 17 Billboard Music Awards, an Academy Award and an MTV Europe Music Global Icon Award. He has had ten number-one albums on the Billboard 200—which all consecutively debuted at number one on the chart, making him the first artist to achieve this and five number-one singles on the Billboard Hot 100
Floyd's breakthrough as a producer came when a number of his beats were used by Florida rapper XXXTENTACION (Jahseh Onfroy, namely the track "Jocelyn Flores", which would peak at Number 19 on the Billboard Hot 100. Potsu co-produced the track with internet musician Shiloh Dynasty, whose song Potsu sampled from Instagram, unofficially titled "i know you so well".
In 2018, he released "Friends", a collaboration with British singer Anne-Marie. Months later, His second studio album, Joytime II, was released with singles "Tell Me" and "Check This Out". "Happier", a collaboration with British band Bastille, was released in August and became his highest charting song on the Billboard Hot 100 at no.2. In 2019, he earned $40 million, ranking second on the list of highest paid DJs compiled by Forbes. In 2020, he and American rapper Juice World released "Come & Go'', from the latter's posthumous album Legends Never Die; the song reached number two on the Billboard Hot 100, matching "Happier" as his highest charting song. In 2021, his album Shockwave earned him a Grammy nomination.